Stabilization of zwitterionic aryltrifluoroborates against hydrolysis.
نویسندگان
چکیده
The presence of a proximal cationic group in zwitterionic aryltrifluoroborates such as o-(Ph(2)MeP)C(6)H(4)(BF(3)) stabilizes these compounds against hydrolysis.
منابع مشابه
Stabilization of zwitterionic versus canonical proline by water molecules.
At physiological conditions, a majority of biomolecules (e.g., amino acids, peptides and proteins) exist predominantly in the zwitterionic form that usually decides the biological functions. However, zwitterionic amino acids are not geometrically stable in gas phase and this seriously hampers the understanding of their structures, properties and biological functions. To this end, one of the rec...
متن کاملA computational study of the glycylserine hydrolysis at physiological pH: a zwitterionic versus anionic mechanism.
The hydrolysis of GlySer at physiological pH was investigated by modeling the most feasible reaction mechanisms in aqueous phase at the MP2/6-311+(2df,2p)//SMD-M06/6-311+(2df,2p) level of the theory. To refine the energies of the most relevant transition states along the reaction paths the cluster-continuum concept was adopted. The hydrolytic process could proceed through two competitive mechan...
متن کاملZwitterionic versus canonical amino acids over the various defects in zeolites: A two-layer ONIOM calculation
Defects are often considered as the active sites for chemical reactions. Here a variety of defects in zeolites are used to stabilize zwitterionic glycine that is not self-stable in gas phase; in addition, effects of acidic strengths and zeolite channels on zwitterionic stabilization are demonstrated. Glycine zwitterions can be stabilized by all these defects and energetically prefer to canonica...
متن کاملPeriodic mesoporous organosilica from zwitterionic precursors.
Mesoporous hybrid silica bearing zwitterionic species were synthesized via template-directed hydrolysis-polycondensation reactions from zwitterionic ammonium sulfonate precursors. The formation of the nanostructured phases involves specific precursor-template interactions. The obtained materials are efficient heterogeneous catalysts in Biginelli reactions.
متن کاملSynchronizing nonfouling and antimicrobial properties in a zwitterionic hydrogel.
In this work, we report a new approach to integrate antimicrobial and nonfouling properties into a single platform without compromising each other. To achieve this, a zwitterionic hydrogel is conjugated with an antimicrobial agent as a leaving group in a way that maintains the zwitterionic form of the hydrogel before, during and after drug release, preventing bacteria surface adhesion and bulk ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 46 34 شماره
صفحات -
تاریخ انتشار 2010